{
  "data": {
    "id": "liraglutide",
    "canonicalName": "Liraglutide",
    "aliases": [],
    "exactForm": "pending",
    "route": "pending",
    "dosageForm": "pending",
    "intendedUse": "human use (unspecified)",
    "productStatus": "FDA-approved: LIRAGLUTIDE (ANDA212552), LIRAGLUTIDE (ANDA212972), LIRAGLUTIDE (ANDA213155), LIRAGLUTIDE (ANDA214568), LIRAGLUTIDE (ANDA215245), LIRAGLUTIDE (ANDA215421), LIRAGLUTIDE (ANDA215503), LIRAGLUTIDE (ANDA217063), LIRAGLUTIDE (ANDA217234), LIRAGLUTIDE (ANDA217590), LIRAGLUTIDE (ANDA218115), SAXENDA (NDA206321), VICTOZA (NDA022341), XULTOPHY 100/3.6 (BLA208583)",
    "compoundingStatus": "Not verified",
    "evidenceTier": "FDA-approved product exists",
    "answer": "Liraglutide has FDA-approved prescription products (LIRAGLUTIDE (ANDA212552), LIRAGLUTIDE (ANDA212972), LIRAGLUTIDE (ANDA213155), LIRAGLUTIDE (ANDA214568), LIRAGLUTIDE (ANDA215245), LIRAGLUTIDE (ANDA215421), LIRAGLUTIDE (ANDA215503), LIRAGLUTIDE (ANDA217063), LIRAGLUTIDE (ANDA217234), LIRAGLUTIDE (ANDA217590), LIRAGLUTIDE (ANDA218115), SAXENDA (NDA206321), VICTOZA (NDA022341), XULTOPHY 100/3.6 (BLA208583)). FDA's drug shortage database lists 10 Liraglutide entries (Current, To Be Discontinued) as of 2026-07-25; that describes supply of an approved product, not whether compounding is lawful. Liraglutide is not on FDA's 503B Bulks List for outsourcing facilities (list checked 2026-07-25). 50 registered ClinicalTrials.gov studies cite Liraglutide (35 completed, 4 recruiting, 4 unknown, 3 not yet recruiting, 3 terminated, 1 active not recruiting); registration is not evidence of approval, efficacy, or safety. CompoundedGuide is verifying compounding status, safety signals, and current evidence. This is not medical advice.",
    "uncertainty": [
      "FDA approval status read from a captured openFDA Drugs@FDA response covering 14 application numbers.",
      "Approval data is not editorially reviewed; it reports what the FDA record says.",
      "Trial counts are read from a captured ClinicalTrials.gov response citing 50 specific study records, not from an open search.",
      "Shortage listings are read from a capture dated 2026-07-25; FDA reverifies them periodically, so this reflects that date rather than today.",
      "503B Bulks List membership was read from the list page captured 2026-07-25; being off that list is not itself a statement that compounding is lawful or unlawful.",
      "Compounding status, shortage status, and safety profile are not yet verified.",
      "This is not a medical, legal, or professional endorsement."
    ],
    "lane": "approved",
    "commercialPolicy": "none",
    "reviewedAt": "2026-07-25",
    "sources": [
      {
        "id": "fda_openfda_drugsfda",
        "title": "openFDA Drugs@FDA",
        "authorityTier": "P0",
        "url": "https://api.fda.gov/drug/drugsfda.json?search=application_number%3A(%22ANDA212552%22%20OR%20%22ANDA212972%22%20OR%20%22ANDA213155%22%20OR%20%22ANDA214568%22%20OR%20%22ANDA215245%22%20OR%20%22ANDA215421%22%20OR%20%22ANDA215503%22%20OR%20%22ANDA217063%22%20OR%20%22ANDA217234%22%20OR%20%22ANDA217590%22%20OR%20%22ANDA218115%22%20OR%20%22BLA208583%22%20OR%20%22NDA022341%22%20OR%20%22NDA206321%22)&limit=50",
        "retrievedAt": "2026-07-25T13:21:06.375Z"
      },
      {
        "id": "fda_openfda_shortages",
        "title": "openFDA Drug Shortages",
        "authorityTier": "P0",
        "url": "https://api.fda.gov/drug/shortages.json?search=package_ndc%3A(%220143-9144-02%22%20OR%20%220143-9144-03%22%20OR%20%220169-2800-15%22%20OR%20%220169-4060-12%22%20OR%20%220169-4060-13%22%20OR%20%220480-3667-20%22%20OR%20%220480-3667-22%22%20OR%20%220480-7250-46%22%20OR%20%2271288-563-84%22%20OR%20%2271288-563-85%22)&limit=100",
        "retrievedAt": "2026-07-25T16:07:49.029Z"
      },
      {
        "id": "fda_503b_bulks",
        "title": "503B Bulks List and Interim Categories",
        "authorityTier": "P0",
        "url": "https://www.fda.gov/drugs/human-drug-compounding/503b-bulk-drug-substances-list",
        "retrievedAt": "2026-07-25T04:39:32.764Z"
      },
      {
        "id": "clinicaltrials_gov_api",
        "title": "ClinicalTrials.gov API v2",
        "authorityTier": "P0",
        "url": "https://clinicaltrials.gov/api/v2/studies?filter.ids=NCT00620282,NCT01179048,NCT01208012,NCT01336023,NCT01373450,NCT01425580,NCT01455441,NCT01473953,NCT01507337,NCT01508897,NCT01511172,NCT01515579,NCT01516476,NCT01517555,NCT01610934,NCT01628445,NCT01755416,NCT01795248,NCT01843075,NCT01974544,NCT02059564,NCT02072096,NCT02138045,NCT02420262,NCT02453711,NCT02518945,NCT02765399,NCT02787551,NCT02931370,NCT02944500,NCT03018028,NCT03036800,NCT03151005,NCT03479762,NCT03486392,NCT03619330,NCT04605861,NCT05153590,NCT05225974,NCT05390892,NCT05419856,NCT05467514,NCT05598008,NCT05681299,NCT05767255,NCT06361238,NCT06559722,NCT06865365,NCT07244003,NCT07613437&pageSize=50&countTotal=true",
        "retrievedAt": "2026-07-25T01:36:44.104Z"
      }
    ],
    "trials": [
      {
        "nctId": "NCT07613437",
        "title": "GLP-1 Receptor Agonist in Primary Intracerebral Hemorrhage: A Phase 2 Randomized Trial",
        "status": "NOT_YET_RECRUITING",
        "phase": "PHASE2",
        "startYear": "2026"
      },
      {
        "nctId": "NCT06865365",
        "title": "Preoperative Use of Liraglutide Additionally to Common Dietological Measures as Opposed to Dietological Measures Alone",
        "status": "NOT_YET_RECRUITING",
        "phase": "PHASE4",
        "startYear": "2025"
      },
      {
        "nctId": "NCT07244003",
        "title": "Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control",
        "status": "RECRUITING",
        "phase": "PHASE4",
        "startYear": "2025"
      },
      {
        "nctId": "NCT06559722",
        "title": "A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes",
        "status": "NOT_YET_RECRUITING",
        "phase": "PHASE3",
        "startYear": "2024"
      },
      {
        "nctId": "NCT06361238",
        "title": "Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery",
        "status": "RECRUITING",
        "phase": "PHASE3",
        "startYear": "2024"
      },
      {
        "nctId": "NCT05681299",
        "title": "Effects of GH and Lirglutide on AgRP",
        "status": "RECRUITING",
        "phase": "PHASE4",
        "startYear": "2023"
      },
      {
        "nctId": "NCT05598008",
        "title": "Effects of Glucagon-like-Peptide-1 Analogues on Sexuality",
        "status": "COMPLETED",
        "phase": "",
        "startYear": "2022"
      },
      {
        "nctId": "NCT05767255",
        "title": "Risk of Hypoglycemia in the Transition From Inpatient to Outpatient Setting. Comparative Study of Basal-bolus Insulin Versus Basal Insulin Plus GLP-1 Analogue",
        "status": "UNKNOWN",
        "phase": "PHASE3",
        "startYear": "2022"
      },
      {
        "nctId": "NCT05390892",
        "title": "PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes",
        "status": "RECRUITING",
        "phase": "PHASE4",
        "startYear": "2022"
      },
      {
        "nctId": "NCT05467514",
        "title": "Effect of Liraglutide on Subclinical Atherosclerosis in Patients With Type 1 Diabetes Mellitus",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2022"
      },
      {
        "nctId": "NCT05419856",
        "title": "Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2022"
      },
      {
        "nctId": "NCT05153590",
        "title": "A Research Study About Weight Loss and Treatment Patterns With the Use of Saxenda® in Adults in Real-life Settings in Switzerland",
        "status": "COMPLETED",
        "phase": "",
        "startYear": "2021"
      },
      {
        "nctId": "NCT05225974",
        "title": "A Randomized Phase 1 Study of Liralutide Injection in Healthy Chinese Subjects",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2021"
      },
      {
        "nctId": "NCT04605861",
        "title": "The Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight Patients",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2020"
      },
      {
        "nctId": "NCT03479762",
        "title": "In Market Utilisation of Liraglutide Used for Weight Management in the UK: a Study in the CPRD Primary Care Database",
        "status": "COMPLETED",
        "phase": "",
        "startYear": "2018"
      },
      {
        "nctId": "NCT03486392",
        "title": "A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Non-diabetic Severely Obese Participants",
        "status": "COMPLETED",
        "phase": "PHASE2",
        "startYear": "2018"
      },
      {
        "nctId": "NCT03151005",
        "title": "The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2017"
      },
      {
        "nctId": "NCT03036800",
        "title": "Saxenda in Obesity Services (STRIVE Study)",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2017"
      },
      {
        "nctId": "NCT03018028",
        "title": "Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2017"
      },
      {
        "nctId": "NCT02787551",
        "title": "Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2016"
      },
      {
        "nctId": "NCT02944500",
        "title": "Saxenda: Underlying Mechanisms and Clinical Outcomes",
        "status": "ACTIVE_NOT_RECRUITING",
        "phase": "PHASE4",
        "startYear": "2016"
      },
      {
        "nctId": "NCT02931370",
        "title": "Ultrasound of the Knee in Obese Patients With Knee Osteoarthritis; Weight Loss",
        "status": "COMPLETED",
        "phase": "",
        "startYear": "2016"
      },
      {
        "nctId": "NCT02518945",
        "title": "Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2015"
      },
      {
        "nctId": "NCT02420262",
        "title": "A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2015"
      },
      {
        "nctId": "NCT02765399",
        "title": "The Effect of Liraglutide Treatment on Postprandial Chylomicron and VLDL Kinetics, Liver Fat and de Novo Lipogenesis",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2015"
      },
      {
        "nctId": "NCT02453711",
        "title": "Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus",
        "status": "COMPLETED",
        "phase": "PHASE2",
        "startYear": "2015"
      },
      {
        "nctId": "NCT03619330",
        "title": "Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2014"
      },
      {
        "nctId": "NCT02072096",
        "title": "A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)",
        "status": "TERMINATED",
        "phase": "PHASE4",
        "startYear": "2014"
      },
      {
        "nctId": "NCT02138045",
        "title": "Treatment of Diabetic Neuropathy With Liraglutide",
        "status": "COMPLETED",
        "phase": "NA",
        "startYear": "2014"
      },
      {
        "nctId": "NCT01843075",
        "title": "Evaluating Liraglutide in Alzheimer's Disease",
        "status": "UNKNOWN",
        "phase": "PHASE2",
        "startYear": "2014"
      },
      {
        "nctId": "NCT01755416",
        "title": "Liraglutide Versus Insulin Mono-therapy in the Closed Loop Setting",
        "status": "COMPLETED",
        "phase": "PHASE2",
        "startYear": "2013"
      },
      {
        "nctId": "NCT01974544",
        "title": "Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines",
        "status": "UNKNOWN",
        "phase": "NA",
        "startYear": "2013"
      },
      {
        "nctId": "NCT02059564",
        "title": "A Phase 1b Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus",
        "status": "UNKNOWN",
        "phase": "PHASE1",
        "startYear": "2013"
      },
      {
        "nctId": "NCT01628445",
        "title": "Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin",
        "status": "TERMINATED",
        "phase": "PHASE3",
        "startYear": "2012"
      },
      {
        "nctId": "NCT01425580",
        "title": "Liraglutide and Heart Failure in Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE2",
        "startYear": "2012"
      },
      {
        "nctId": "NCT01610934",
        "title": "The Effects of GLP-1 in Maturity-Onset Diabetes of The Young (MODY)",
        "status": "COMPLETED",
        "phase": "PHASE2/PHASE3",
        "startYear": "2012"
      },
      {
        "nctId": "NCT01795248",
        "title": "The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2012"
      },
      {
        "nctId": "NCT01473953",
        "title": "Safety, Tolerability and Pharmacokinetics of Liraglutide-depot in Healthy Subjects",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2011"
      },
      {
        "nctId": "NCT01455441",
        "title": "The Effects of Physical Training and GLP-1 Receptor Agonist Liraglutide Treatment in Patients With Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2011"
      },
      {
        "nctId": "NCT01516476",
        "title": "Study of RO6807952 in Patients With Diabetes Mellitus Type 2",
        "status": "TERMINATED",
        "phase": "PHASE2",
        "startYear": "2011"
      },
      {
        "nctId": "NCT01336023",
        "title": "Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2011"
      },
      {
        "nctId": "NCT01373450",
        "title": "Evaluation of the Glucoregulatory Effects of Glucagon-like Peptide-1 Receptor (GLP-1 Receptor) Activation in Participants With Type 2 Diabetes Mellitus (MK-0000-222)",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2011"
      },
      {
        "nctId": "NCT01208012",
        "title": "Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus",
        "status": "COMPLETED",
        "phase": "PHASE4",
        "startYear": "2010"
      },
      {
        "nctId": "NCT01179048",
        "title": "Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2010"
      },
      {
        "nctId": "NCT00620282",
        "title": "The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes Mellitus",
        "status": "COMPLETED",
        "phase": "PHASE3",
        "startYear": "2008"
      },
      {
        "nctId": "NCT01515579",
        "title": "Comparison of Two Liraglutide Formulations in Healthy Subjects",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2006"
      },
      {
        "nctId": "NCT01517555",
        "title": "Effect of Liraglutide on Absorption of Paracetamol in Subjects With Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2006"
      },
      {
        "nctId": "NCT01507337",
        "title": "Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy Volunteers",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2004"
      },
      {
        "nctId": "NCT01508897",
        "title": "Comparison of Two Liraglutide Formulations in Healthy Volunteers",
        "status": "COMPLETED",
        "phase": "PHASE1",
        "startYear": "2004"
      },
      {
        "nctId": "NCT01511172",
        "title": "Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 Diabetes",
        "status": "COMPLETED",
        "phase": "PHASE2",
        "startYear": "2002"
      }
    ],
    "pendingResources": {
      "identity": [
        "FDA/NCATS GSRS or equivalent canonical identity source"
      ],
      "product_status": [
        "Drugs@FDA, Purple Book, Orange Book, DailyMed, or applicable primary FDA record"
      ],
      "compounding_status": [
        "FDA 503A/503B pages, Federal Register, docket, or applicable final/interim policy"
      ],
      "safety": [
        "FDA safety communication, warning, recall, FAERS signal context, or explicit absence statement"
      ],
      "evidence": [
        "ClinicalTrials.gov and PubMed/primary publication search"
      ],
      "state_or_facility": [
        "State board or FDA facility record when relevant"
      ]
    }
  }
}